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Bcl-3, a proto-oncogene, is believed to be involved in certain human B cell leukemias. It encodes a protein that functions as an IkB -like molecule for native NFkB, but is specific for the p50 subunit of NFkB. Numero articolo: BIOV3407-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage	BLK, a BH3-containing protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist. Numero articolo: BIOV3175-100 Unità di misura: 100 MCG Imballaggio: Vial 360,00 CHF 360.0 CHF Aktuelle Lieferfrist auf Anfrage	Paxillin is one of the key components of integrin signaling. Tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization. Paxillin is phosphorylated by another focal adhesion component, focal adhesion Numero articolo: BIOV3448-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	Bcl-6 encodes a protein of 706 amino acids with a predicted molecular weight of 79 kDa. The Bcl-6 protein has homology with zinc fin ger transcription factors. However, little is known about its functions. Numero articolo: BIOV3408-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Aktuelle Lieferfrist auf Anfrage
PDK1 (Phosphoinositide-dependent protein kinase 1) plays an important role in cell signaling pathways and is involved in regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis. Numero articolo: BIOV3449-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	p53DINP1 (p53-dependent damage-inducible nuclear protein 1) encodes two proteins termed p53DINP1-α (27 kDa) and p53DINP1-β (18 kDa). p53DINP1 may regulate p53-dependent apoptosis throμgh phosphorylation at Ser46 and induction of p53AIP1. p5 Numero articolo: BIOV3340-100 Unità di misura: 100 MCG Imballaggio: Vial 322,00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase-9/Apaf-1. Numero articolo: BIOV3409-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	HADH (Hydroxyacyl-Coenzyme A dehydrogenase) is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids , alcohols, and steroids. 3-hydroxyacyl-CoA dehydrogenase type II (HADH2) is a member of the short-chain deh Numero articolo: BIOV3246-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All Numero articolo: BIOV3342-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	PKC (Protein kinase C) is a calcium-dependent and phospholipid-dependent enzyme that is activated in vivo by the lipid diacylglycero l. PKC has been shown to be involved in signal transduction and various aspects of neoplastic transformation Numero articolo: BIOV3451-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstrea m effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase Numero articolo: BIOV3248-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	PKGs are cyclic GMP-dependent protein kinases (also designed cGKs) that are classified into two types, PKGI and PKGII. Studies have shown that cGKs and cyclic AMP-dependent kinases (cAKs) are highly homologous protein kinase families Numero articolo: BIOV3452-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage
Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in pa ired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheim Numero articolo: BIOV3453-100 Unità di misura: 100 4G Imballaggio: Vial 455,00 CHF 455.0 CHF Aktuelle Lieferfrist auf Anfrage	IkB-alpha protein is a NF-kB inhibitory protein. It binds NF-kB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus and functioning as a transcription factor. Upon receiving a variety of signals, IkB-a Numero articolo: BIOV3252-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase that is closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, hormones, and osmotic shock, etc. Numero articolo: BIOV3459-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	ACAA2 (acetylcoenzyme A acyltransferase 2), is member of the thiolase family of enzymes and is involved in lipid metabolism. ACAA2 i s localized in the mitochondria. ACCA2 catalyzes the last conversion step of acetyl-CoA to 3-oxoacyl-CoA, in Numero articolo: BIOV3538-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3461-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cat hepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Numero articolo: BIOV3412-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3464-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of T GFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function Numero articolo: BIOV3465-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage

VWR / Merck Prodotti chimici