Mirin is a small-molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex. Mirin blocks the 3' and 5' exonuclease activity associ ated with Mre11. Prevents ATM activation in response to double strand breaks (IC₅₀ = 12 μM) and induces G2 cell cycle
Numero articolo: BIOVB1075-10
Unità di misura: 10 MG
Produttore: BIOVISION
Numero del produttore: B1075-10
Temperatura di stoccaggio: Freezer (-20)
Mirin is a small-molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex. Mirin blocks the 3' and 5' exonuclease activity associ ated with Mre11. Prevents ATM activation in response to double strand breaks (IC₅₀ = 12 μM) and induces G2 cell cycle
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