LDE225 is a potent and selective antagonist of Smoothened (Smo) with IC₅₀ values of 2.5 nM and 1.3 nM for human and mouse Hedgehog, respectively. LDE-225 induces dose-related inhibition of Hh and Smo-dependent tumour growth.

Numero articolo: BIOV2892-5
Unità di misura: 5 MG
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    Produttore: BIOVISION
    Numero del produttore: 2892-5
    Temperatura di stoccaggio: Freezer (-20)

    LDE225 is a potent and selective antagonist of Smoothened (Smo) with IC₅₀ values of 2.5 nM and 1.3 nM for human and mouse Hedgehog, respectively. LDE-225 induces dose-related inhibition of Hh and Smo-dependent tumour growth.