LDE225 is a potent and selective antagonist of Smoothened (Smo) with IC₅₀ values of 2.5 nM and 1.3 nM for human and mouse Hedgehog, respectively. LDE-225 induces dose-related inhibition of Hh and Smo-dependent tumour growth.

Numéro d'article : BIOV2892-25
Unité de mesure : 25 MG
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    Numéro du fabricant : 2892-25
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    LDE225 is a potent and selective antagonist of Smoothened (Smo) with IC₅₀ values of 2.5 nM and 1.3 nM for human and mouse Hedgehog, respectively. LDE-225 induces dose-related inhibition of Hh and Smo-dependent tumour growth.