An orally active, selective inhibitor of Cdk4 (IC50 = 11 nM) and Cdk6 (IC50 = 16 nM) with antiproliferative activity against retinob lastoma-positive tumor cells, blocking retinoblastoma phosphorylation and inducing G1 arrest, UoM: 1 * 5 mg, CAS: 827022-32-2

Item Number: CAYM16273-5
Unit of Measure: 5 MG
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    CAS Number: 827022-32-2
    Manufacturer: CAYMAN
    Manufacturer Number: 16273-5
    Chemical Formula: C24H29N7O2•HCl
    Storage Temperature: Freezer (-20)

    An orally active, selective inhibitor of Cdk4 (IC50 = 11 nM) and Cdk6 (IC50 = 16 nM) with antiproliferative activity against retinob lastoma-positive tumor cells, blocking retinoblastoma phosphorylation and inducing G1 arrest, UoM: 1 * 5 mg, CAS: 827022-32-2