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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an accept or amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal tr Numero articolo: BIOV3152-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta	Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases ( PRMTs). PRMT6 catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side Numero articolo: BIOV3086-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	GSAP, gamma-secretase activating protein interacts with gamma secretase which chops up the amyloid precursor protein to senile plaqu es in Alzheimer’s disease. GSAP was found to increase the production amyloid peptide. Immunohistochemistry t Numero articolo: BIOV3308-100 Unità di misura: 100 MCG Imballaggio: Vial 347,00 CHF 347.0 CHF Tempo di consegna attuale su richiesta	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative spl icing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic isl Numero articolo: BIOV3153-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative spl icing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic isl Numero articolo: BIOV3154-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta	The GLB1 gene encodes beta-galactosidase-1 (EC 3.2.1.23), a lysosomal hydrolase that cleaves the terminal beta-galactose from gangli oside substrates and other glycoconjugates (Yoshida et al., 1991 [PubMed 1907800]). Numero articolo: BIOV3231-100 Unità di misura: 100 MCG Imballaggio: Vial 347,00 CHF 347.0 CHF Tempo di consegna attuale su richiesta	Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also sy nthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Numero articolo: BIOV3156-100 Unità di misura: 100 MCG Imballaggio: Vial 429,00 CHF 429.0 CHF Tempo di consegna attuale su richiesta	The mammalian proto-oncogene Ras encodes 21 kDa proteins (p21Ras) which exists in either a physiologically quiescent GDP-binding sta te or a GTPbinding signal-emitting state. Interaction of p21Ras with GTPase activating protein (GAP) Numero articolo: BIOV3311-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes catalyze the dehydrogena tion of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Numero articolo: BIOV3157-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414 amino acids protein Numero articolo: BIOV3232-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Heme oxygenase-1 (HO-1) or HSP32 is the inducible isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reduct ase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilir Numero articolo: BIOV3391-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta	TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development, TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. Numero articolo: BIOV3088-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Bcl-xL is a 30 kDa anti-apoptotic protein belonging to the Bcl-2 family. Bcl-xL prevents apoptosis throμgh two different mechanisms: by heterodimerization with an apoptotic protein to inhibit its apoptotic effect, and by its direct pore-for Numero articolo: BIOV3312-100 Unità di misura: 100 MCG Imballaggio: Vial 360,00 CHF 360.0 CHF Tempo di consegna attuale su richiesta	Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two he me oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. Numero articolo: BIOV3392-100 Unità di misura: 100 MCG Imballaggio: Vial 354,00 CHF 354.0 CHF Tempo di consegna attuale su richiesta	KLF4 belongs to the erythroid Kruppel-like factor (EKLF) family that is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Numero articolo: BIOV3089-200 Unità di misura: 200 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10 Numero articolo: BIOV3313-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta
Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue spec ific cell fate during embryogenesis, like muscle or early B cell differentiation. Numero articolo: BIOV3090-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. Numero articolo: BIOV3393-100 Unità di misura: 100 MCG Imballaggio: Vial 391,00 CHF 391.0 CHF Tempo di consegna attuale su richiesta	CIKS (for connection to IKK and SAPK/JNK), also called Act1 (for NF-kB activator 1), is a novel protein that associates with and act ivates IKK (IkB kinase). CIKS/Act1 also activates ATF (activating transcription factor) and AP-1 (activator Numero articolo: BIOV3314-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzyma tic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically Numero articolo: BIOV3171-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici