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Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue spec ific cell fate during embryogenesis, like muscle or early B cell differentiation. Numero articolo: BIOV3090-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. Numero articolo: BIOV3393-100 Unità di misura: 100 MCG Imballaggio: Vial 391,00 CHF 391.0 CHF Tempo di consegna attuale su richiesta	CIKS (for connection to IKK and SAPK/JNK), also called Act1 (for NF-kB activator 1), is a novel protein that associates with and act ivates IKK (IkB kinase). CIKS/Act1 also activates ATF (activating transcription factor) and AP-1 (activator Numero articolo: BIOV3314-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzyma tic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically Numero articolo: BIOV3171-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta
Erk-5 shares high homology in the amino-terminal kinase domain with Erk1/2. However, the long carboxy-terminal kinase domain makes E rk5 a unique MAP kinase. Erk5 is activated by a variety of extracellular signals. The direct upstream kinase Numero articolo: BIOV3397-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. IkB proteins are phosphorylated by IkB kinase complex consisting o f at least three proteins, IKK1/α, IKK2/β, and IKK3/g. External stimuli such TNF-α or other cytokines result Numero articolo: BIOV3315-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Tempo di consegna attuale su richiesta	Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or F as ligand (FasL). FasL is a tumor necrosis factor (TNF)-related type II membrane protein and is expressed in Numero articolo: BIOV3330-100 Unità di misura: 100 MCG Imballaggio: Vial 373,00 CHF 373.0 CHF Tempo di consegna attuale su richiesta	LIN28 is a highly conserved cytoplasmic RNAbinding protein. Lin28 has an N-terminal cold shock domain and two Cterminal (CCHC) zin c finger motif. It is expressed in embryonic stem cells and embryonic carcinoma cells. Numero articolo: BIOV3091-200 Unità di misura: 200 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta
Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers, but undetectable in terminally differenti ated adult tissues. It has been shown that recombinant expression of Survivin conteracts apoptosis of B lymp Numero articolo: BIOV3161-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	TCTN3 belongs to the Tectonic protein family that regulate the Hedgehog (Hh)-signaling pathway. While the expression pattern and fun ction of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is required for the formation of most ventral Numero articolo: BIOV3333-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Etk is a member of the Bruton’s tyrosine kinase family. Etk is expressed in a variety of hematopoietic, epithelial and endothelial c ells. It participates in multiple signal transduction pathways. Phosphorylation of tyrosine 566 by Src kinas Numero articolo: BIOV3398R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic developmen t and in the determination of the cell fate. The protein may act as a transcriptional regulator after formin Numero articolo: BIOV3168-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta
The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Several mechanisms that induce PAK ac Numero articolo: BIOV3444-100 Unità di misura: 100 MCG Imballaggio: Vial 328,00 CHF 328.0 CHF Tempo di consegna attuale su richiesta	Bmf (for Bcl-2-modifying factor) is a novel BH3-only protein recently identified in human and mouse. The BH3 domain in Bmf is requir ed for both binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Numero articolo: BIOV3334R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Focal adhesion kinase was identified as a 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase Numero articolo: BIOV3399-100 Unità di misura: 100 MCG Imballaggio: Vial 335,00 CHF 335.0 CHF Tempo di consegna attuale su richiesta	AMPK2 alpha2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha cataly tic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that moni Numero articolo: BIOV3169-100 Unità di misura: 100 MCG Imballaggio: Vial 410,00 CHF 410.0 CHF Tempo di consegna attuale su richiesta
Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers, but undetectable in terminally differenti ated adult tissues. It has been shown that recombinant expression of Survivin counteracts apoptosis of B lym Numero articolo: BIOV3170-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	Endonuclease G (EndoG) is a mitochondrion-specific nuclease that specifically activated by apoptotic stimuli and translocates to the nucleus during apoptosis. In nucleus, EndoG induces nucleosomal fragmentation of DNA independent of caspase Numero articolo: BIOV3336R-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta	NORDIHYDROGUAIARETIC ACID, UoM: 1 * 500 mg, CAS: 500-38-9 Numero articolo: CAYM70300-500 Unità di misura: 500 MG Imballaggio: Glass bottle for solids 73,10 CHF 73.10000000000001 CHF Tempo di consegna attuale su richiesta	ILP-2 (for IAP-like protein-2) is a novel member of in the IAP (Inhibitor of Apoptosis) protein family. ILP-2 has high homology to I LP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. Numero articolo: BIOV3337-100 Unità di misura: 100 MCG Imballaggio: Vial 309,00 CHF 309.0 CHF Tempo di consegna attuale su richiesta

VWR / Merck Prodotti chimici