R428 is a potent and selective small-molecule inhibitor (IC₅₀ = 14 nM) of the receptor tyrosine kinase Axl. R428 blocks Axl-dependen t events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production.
Numero articolo: BIOV9591-25
Unità di misura: 25 MG
R428 is a potent and selective small-molecule inhibitor (IC₅₀ = 14 nM) of the receptor tyrosine kinase Axl. R428 blocks Axl-dependen t events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production.
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