IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.
Numero articolo: BIOV2822-25
Unità di misura: 25 MG
Numero CAS: 1129669-05-1
Produttore: BIOVISION
Numero del produttore: 2822-25
Formula chimica: C22H20FN3O2
Temperatura di stoccaggio: Freezer (-20)
IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.
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