PLX-4720 is a potent, ATP-competitive B-raf inhibitor (IC₅₀ =160 nM). PLX-4720 preferentially inhibits the active B-Raf(V600E) kinas e compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing t

Numero articolo: BIOV2813-5
Unità di misura: 5 MG
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    Produttore: BIOVISION
    Numero del produttore: 2813-5
    Temperatura di stoccaggio: Freezer (-20)

    PLX-4720 is a potent, ATP-competitive B-raf inhibitor (IC₅₀ =160 nM). PLX-4720 preferentially inhibits the active B-Raf(V600E) kinas e compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing t