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The caspase family of cysteine proteases play a key role in apoptosis. Caspase-3 is the most extensively studied apoptotic protein a mong caspase family members. Numéro d'article : BIOV3004-100 Unité de mesure : 100 MCG Emballage : Vial 391.00 CHF 391.0 CHF Aktuelle Lieferfrist auf Anfrage	Cathepsin D is a normal lysosomal protease that is expressed in all cells. It is an aspartyl protease with a pH optimum in the range of 3-5, and contains two N-linked oligosaccharides. Cathepsin D is synthesized as an inactive 52 kDa pro Numéro d'article : BIOV3191R-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of α- and β-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. α-Fodrin is one of Numéro d'article : BIOV3266-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be p rocessed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21 Numéro d'article : BIOV3192-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage
Wee1 is a nuclear tyrosine protein kinase. The protein plays a role in suppressing eukaryotes’ entry into mitosis by inactivating cd c2 kinase by inhibiting tyrosine phosphorylation. The predicted molecular weight of the kinase is 72 kDa. Numéro d'article : BIOV3120-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK w as initially isolated from a human B cell cDNA library and contains 795 amino acids with an apparent molecul Numéro d'article : BIOV3193R-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	FATP4 is a transmembrane protein that is involved in the uptake and metabolism of long chain fatty acids. FATP4 has acyl-CoA synth ase activity and contains an AMP-binding motif. FATP4 is linked to insulin resistance and metabolic disorde Numéro d'article : BIOV3268-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 forms homo dimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr6 Numéro d'article : BIOV3359-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage
Bad is a member of the Bcl-2 family protein that selectively dimerize with Bcl-xL and Bcl-2 resulting in cell death. Survival factor s such as IL-3 can inhibit the apoptotic activity of Bad by activating intracellular signaling pathways that Numéro d'article : BIOV3269-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Aktuelle Lieferfrist auf Anfrage	Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellula r signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors Numéro d'article : BIOV3360R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Histone-lysine N- methyltransferase SETD3 has a function as methylation of Lys36 of histone H3 which represents a specific tag for e pigenetic transcriptional activation. It is highly expressed in muscular tissues. Numéro d'article : BIOV3197-200 Unité de mesure : 200 MCG Emballage : Vial 347.00 CHF 347.0 CHF Aktuelle Lieferfrist auf Anfrage	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encod es hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose- Numéro d'article : BIOV3198-100 Unité de mesure : 100 MCG Emballage : Vial 360.00 CHF 360.0 CHF Aktuelle Lieferfrist auf Anfrage
Tumor Necrosis Factor-alpha (TNF-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and cer tain other target cells. Rat TNF-α is a 17 kDa protein containing 157 amino acid residues. Numéro d'article : BIOV3054-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control , DNA replication and chromatin organization. Numéro d'article : BIOV3267-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Arginine methylation is an important protein modification catalyzed by arginine methyltransferase such as PRMT7. PRMT7 has two methy ltransferase domains each containing a putative AdoMet binding motif. Numéro d'article : BIOV3059-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. Numéro d'article : BIOV3199-100 Unité de mesure : 100 MCG Emballage : Vial 347.00 CHF 347.0 CHF Aktuelle Lieferfrist auf Anfrage
Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. BLCAM α and BLCAM β are p Numéro d'article : BIOV3363-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death . Numéro d'article : BIOV3201-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	Apoptosis can be induced by certain cytokines including TNF and Fas Ligand of the TNF super-family throμgh their death domain (DD) c ontaining receptors, TNFR1 and Fas. Numéro d'article : BIOV3061R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	MAK10 protein regulates the proliferation of smooth muscle cells. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. Numéro d'article : BIOV3134-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage

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