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Focal adhesion kinase was identified as a 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase Numéro d'article : BIOV3399-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	AMPK2 alpha2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha cataly tic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that moni Numéro d'article : BIOV3169-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Délai de livraison actuel sur demande	Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers, but undetectable in terminally differenti ated adult tissues. It has been shown that recombinant expression of Survivin counteracts apoptosis of B lym Numéro d'article : BIOV3170-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	Endonuclease G (EndoG) is a mitochondrion-specific nuclease that specifically activated by apoptotic stimuli and translocates to the nucleus during apoptosis. In nucleus, EndoG induces nucleosomal fragmentation of DNA independent of caspase Numéro d'article : BIOV3336R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande
NORDIHYDROGUAIARETIC ACID Numéro d'article : CAYM70300-500 Unité de mesure : 500 MG Emballage : Glass bottle for solids 65.70 CHF 65.7 CHF Délai de livraison actuel sur demande	ILP-2 (for IAP-like protein-2) is a novel member of in the IAP (Inhibitor of Apoptosis) protein family. ILP-2 has high homology to I LP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. Numéro d'article : BIOV3337-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial p athogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA Numéro d'article : BIOV3445R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	$Bid, a BH3 domain-containing proapoptotic Bcl-2 family member, is localized in the cytosolic fraction of cells as an inactive precur sor. Its active form is generated upon proteolytic cleavage by caspase-8 in the Fas signaling pathway.$ Bid, a BH3 domain-containing proapoptotic Bcl-2 family member, is localized in the cytosolic fraction of cells as an inactive precur sor. Its active form is generated upon proteolytic cleavage by caspase-8 in the Fas signaling pathway. Numéro d'article : BIOV3172-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande
Five ionomycin-inducible complementary cDNAs, designated PAR1, 2, 3, 4 and 5, have been isolated from the prostate cancer cell line AT-3. Nucleotide sequencing identified PAR1 as the rat homolog of monkeyP-1, PAR2 as the injury-inducible ge Numéro d'article : BIOV3447-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	The TLR (toll-like receptors) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essenti al for Toll-induced signal transduction. TLR1, as well as the other TLR family members Numéro d'article : BIOV3446-100 Unité de mesure : 100 4G Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	Livin is a novel member in the IAP (inhibitor of apoptosis) protein family. Livin contains a single baculoviral IAP repeat (BIR) dom ain and a RING finger domain and has two isoforms termed Livin-α and Livin-β. Transfection of Livin protecte Numéro d'article : BIOV3338-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 recep tor complex in response to IL-1 treatment. Dominant-negative form of MyD88 attenuates IL-1R-mediated NF-B a Numéro d'article : BIOV3244R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande
Bcl-3, a proto-oncogene, is believed to be involved in certain human B cell leukemias. It encodes a protein that functions as an IkB -like molecule for native NFkB, but is specific for the p50 subunit of NFkB. Numéro d'article : BIOV3407-100 Unité de mesure : 100 MCG Emballage : Vial 354.00 CHF 354.0 CHF Délai de livraison actuel sur demande	PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzyma tic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically Numéro d'article : BIOV3174-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Délai de livraison actuel sur demande	PUMA (p53 upregulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members which are also transcriptional target s of p53. PUMA gene encodes two BH3 domain-containing proteins termed PUMA-α and PUMA-β. PUMA proteins bind Numéro d'article : BIOV3339-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	BLK, a BH3-containing protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist. Numéro d'article : BIOV3175-100 Unité de mesure : 100 MCG Emballage : Vial 360.00 CHF 360.0 CHF Délai de livraison actuel sur demande
Paxillin is one of the key components of integrin signaling. Tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization. Paxillin is phosphorylated by another focal adhesion component, focal adhesion Numéro d'article : BIOV3448-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	Bcl-6 encodes a protein of 706 amino acids with a predicted molecular weight of 79 kDa. The Bcl-6 protein has homology with zinc fin ger transcription factors. However, little is known about its functions. Numéro d'article : BIOV3408-100 Unité de mesure : 100 MCG Emballage : Vial 354.00 CHF 354.0 CHF Délai de livraison actuel sur demande	Members of the Bcl-2 family of proteins interact to regulate programmed cell death, or apoptosis. Various homodimers and heterodimer s formed by proteins in this family can either promote or inhibit apoptosis. Numéro d'article : BIOV3176-100 Unité de mesure : 100 MCG Emballage : Vial 360.00 CHF 360.0 CHF Délai de livraison actuel sur demande	PDK1 (Phosphoinositide-dependent protein kinase 1) plays an important role in cell signaling pathways and is involved in regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis. Numéro d'article : BIOV3449-100 Unité de mesure : 100 MCG Emballage : Vial 322.00 CHF 322.0 CHF Délai de livraison actuel sur demande

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