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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an accept or amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal Numéro d'article : BIOV3146-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Délai de livraison actuel sur demande	Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/c aspase-9 pathway. Smac/DIABLO binds to IAPs (Inhibitor of Apoptosis Proteins) and neutralizes the inhibitor Numéro d'article : BIOV3298-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	Cytochrome P450 is mainly found in liver, and can metabolize a wide range of compounds such as organic solvents, acetaminophen, dime thylnitrosoamine and aliphatic alcohol, which have certain toxicological effects in humans. Numéro d'article : BIOV3084R-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	D4-GDI (GDP dissociation inhibitor) is a negative regulator of the ras-related Rho family of GTPases. Since the Rho GTPases promote cytoskeleytal and membrane changes associated with apoptotic cell death, the removal of the D4-GDI block thr Numéro d'article : BIOV3385-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande
Elk-1 is a transcription factor that binds the serum response element (SRE) and mediates gene activity in response to serum and grow th factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MA Numéro d'article : BIOV3387-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydr ogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Numéro d'article : BIOV3150-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. A major function of HSP90 and other HSPs is to act as molecu lar chaperones. HSP90 forms a complex with glucocorticoid receptor (GR), rendering the non ligand-bound rece Numéro d'article : BIOV3389-100 Unité de mesure : 100 MCG Emballage : Vial 354.00 CHF 354.0 CHF Délai de livraison actuel sur demande	Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases ( PRMTs). PRMT6 catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side Numéro d'article : BIOV3086-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative spl icing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic isl Numéro d'article : BIOV3154-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Délai de livraison actuel sur demande	Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also sy nthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Numéro d'article : BIOV3156-100 Unité de mesure : 100 MCG Emballage : Vial 429.00 CHF 429.0 CHF Délai de livraison actuel sur demande	Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes catalyze the dehydrogena tion of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Numéro d'article : BIOV3157-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414 amino acids protein Numéro d'article : BIOV3232-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande
Heme oxygenase-1 (HO-1) or HSP32 is the inducible isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reduct ase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilir Numéro d'article : BIOV3391-100 Unité de mesure : 100 MCG Emballage : Vial 354.00 CHF 354.0 CHF Délai de livraison actuel sur demande	TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development, TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. Numéro d'article : BIOV3088-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	Bcl-xL is a 30 kDa anti-apoptotic protein belonging to the Bcl-2 family. Bcl-xL prevents apoptosis throμgh two different mechanisms: by heterodimerization with an apoptotic protein to inhibit its apoptotic effect, and by its direct pore-for Numéro d'article : BIOV3312-100 Unité de mesure : 100 MCG Emballage : Vial 360.00 CHF 360.0 CHF Délai de livraison actuel sur demande	Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two he me oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. Numéro d'article : BIOV3392-100 Unité de mesure : 100 MCG Emballage : Vial 354.00 CHF 354.0 CHF Délai de livraison actuel sur demande
KLF4 belongs to the erythroid Kruppel-like factor (EKLF) family that is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Numéro d'article : BIOV3089-200 Unité de mesure : 200 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10 Numéro d'article : BIOV3313-100 Unité de mesure : 100 MCG Emballage : Vial 335.00 CHF 335.0 CHF Délai de livraison actuel sur demande	Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue spec ific cell fate during embryogenesis, like muscle or early B cell differentiation. Numéro d'article : BIOV3090-100 Unité de mesure : 100 MCG Emballage : Vial 309.00 CHF 309.0 CHF Délai de livraison actuel sur demande	PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzyma tic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically Numéro d'article : BIOV3171-100 Unité de mesure : 100 MCG Emballage : Vial 410.00 CHF 410.0 CHF Délai de livraison actuel sur demande

VWR / Merck Produits chimiques