NSC-59984 is a p53 pathway activator that induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. The EC₅₀ of NSC-59984 in most cancer cells is significantly lower than those of normal cells, with EC₅₀ of 8.38 μM for p53
Numéro d'article : BIOVB1052-25
Unité de mesure : 25 MG
NSC-59984 is a p53 pathway activator that induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. The EC₅₀ of NSC-59984 in most cancer cells is significantly lower than those of normal cells, with EC₅₀ of 8.38 μM for p53
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