HTH-01-015 is a potent and selective inhibitor of NUAK1 kinase (IC₅₀ =100 nM); only weakly inhibits NUAK2 (IC₅₀ of >10 μM) and does not significantly inhibit the activity of 139 other kinases that were tested including ten AMPK family members.
Numéro d'article : BIOV2887-5
Unité de mesure : 5 MG
HTH-01-015 is a potent and selective inhibitor of NUAK1 kinase (IC₅₀ =100 nM); only weakly inhibits NUAK2 (IC₅₀ of >10 μM) and does not significantly inhibit the activity of 139 other kinases that were tested including ten AMPK family members.
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