GSK2118436 is a selective BRAF V600E inhibitor. GSK2118436 binds to Raf family kinases and inhibits their activity. It is highly sel ective against B-Raf V600E with IC₅₀ of 0.8 nM, compared to wild type B-Raf and c-Raf with IC₅₀s of 3.2 nM and 5.0 nM
Numéro d'article : BIOV2800-5
Unité de mesure : 5 MG
GSK2118436 is a selective BRAF V600E inhibitor. GSK2118436 binds to Raf family kinases and inhibits their activity. It is highly sel ective against B-Raf V600E with IC₅₀ of 0.8 nM, compared to wild type B-Raf and c-Raf with IC₅₀s of 3.2 nM and 5.0 nM
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