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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encod es hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose- Item Number: BIOV3198-100 Unit of Measure: 100 MCG Packaging: Vial 360.00 CHF 360.0 CHF Current delivery time on request	Tumor Necrosis Factor-alpha (TNF-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and cer tain other target cells. Rat TNF-α is a 17 kDa protein containing 157 amino acid residues. Item Number: BIOV3054-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control , DNA replication and chromatin organization. Item Number: BIOV3267-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Arginine methylation is an important protein modification catalyzed by arginine methyltransferase such as PRMT7. PRMT7 has two methy ltransferase domains each containing a putative AdoMet binding motif. Item Number: BIOV3059-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. Item Number: BIOV3199-100 Unit of Measure: 100 MCG Packaging: Vial 347.00 CHF 347.0 CHF Current delivery time on request	Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting, and is essenti al for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation o Item Number: BIOV3275-100 Unit of Measure: 100 MCG Packaging: Vial 347.00 CHF 347.0 CHF Current delivery time on request	Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. BLCAM α and BLCAM β are p Item Number: BIOV3363-100 Unit of Measure: 100 MCG Packaging: Vial 322.00 CHF 322.0 CHF Current delivery time on request	Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death . Item Number: BIOV3201-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request
Apoptosis can be induced by certain cytokines including TNF and Fas Ligand of the TNF super-family throμgh their death domain (DD) c ontaining receptors, TNFR1 and Fas. Item Number: BIOV3061R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	STATs (signal transducers and activators of transcription) are a family of cytoplamic latent transcription factors that are activate d to regulate gene expression in response to a large number of extracellular signalling peptides including Item Number: BIOV3133R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molec Item Number: BIOV3277-100 Unit of Measure: 100 MCG Packaging: Vial 221.00 CHF 221.0 CHF Current delivery time on request	MAK10 protein regulates the proliferation of smooth muscle cells. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. Item Number: BIOV3134-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request
RIP (Receptor Interacting Protein) is a 74 kDa Ser/Thr kinase which interacts with CD95 (Fas/Apo1) receptor and the tumor necrosis f actor receptor (TNFR1). It is a cell death domain adapter protein which can bind to the adapter proteins TRA Item Number: BIOV3279-100 Unit of Measure: 100 MCG Packaging: Vial 322.00 CHF 322.0 CHF Current delivery time on request	Members of Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) do main is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, H Item Number: BIOV3205-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Cadherins comprise a family of Ca-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenanc e of tissue structure and morphogenesis. Cadherins consist of large extracellular domains characterized by a Item Number: BIOV3365R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Caspase-7 is a 34 kDa protein consisting of two subunits and a short prodomain. The procaspase-7 can be activated by cleavage by ups tream caspases to form active caspase-7 in apoptosis. Item Number: BIOV3135-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request
Stage-Specific Embyronic Antigen-1(SSEA-1), also referred to as Lewis X (LeX), is expressed on murine and human germ cells, murine e mbryonic stem (ES) cells and murine embryonal carcinoma (EC) cells . Item Number: BIOV3063-25 Unit of Measure: 25 MCG Packaging: Vial 259.00 CHF 259.0 CHF Current delivery time on request	The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD1 (methyl-CpG binding domain protein 1) binds to methylated CpG sites and represses gene transcription. Item Number: BIOV3281-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	This antibody reacts with the Stage-specific embryonic antigen-3 (SSEA-3). The epitope is expressed on the surface of human teratoca rcinoma stem cells , embryonic carcinoma (EC) cells, human embryonic germ(EG) cells and human embryonic stem Item Number: BIOV3065-25 Unit of Measure: 25 MCG Packaging: Vial 272.00 CHF 272.0 CHF Current delivery time on request	Nestin may play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daμghter cells d uring progenitor cell division (By similarity). Item Number: BIOV3208-100 Unit of Measure: 100 MCG Packaging: Vial 360.00 CHF 360.0 CHF Current delivery time on request

VWR / Merck Chemicals