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The IRAK family members play an important role in IL-1R/TLR mediated inflammatory responses and in innate immunity. IRAK-4 is a nove l member in the IRAK family. Over expression of IRAK-4 activates NFkB and MAPK pathways. Item Number: BIOV3580-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	GERANIOL Item Number: ICNA0215718410 Unit of Measure: 10 ML Packaging: Glass bottle 51.30 CHF 51.300000000000004 CHF Aktuelle Lieferfrist auf Anfrage	Valosin containing protein (VCP), also designated TERA (for transitional endoplasmic reticulum ATPase) or p97, is a member of the AA A family of ATPases, which are involved in a variety of cellular activities. VCP is the mammalian homolog Item Number: BIOV3756-100 Unit of Measure: 100 4G Packaging: Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	XLF (also called Cernunnos) interacts with the XRCC4-DNA ligase IV complex to promote DNA non-homologous end-joining. It directly in teracts with the XRCC4-Ligase IV complex and siRNA-mediated downregulation of XLF in human cell lines leads Item Number: BIOV3757-100 Unit of Measure: 100 4G Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Selectins are a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. E-Selectin (als o called ELMA-1) expressed on endothelial cells. Item Number: BIOV3633R-100 Unit of Measure: 100 MCG Packaging: Vial 379.00 CHF 379.0 CHF Aktuelle Lieferfrist auf Anfrage	Proteins of the matrix metalloprotease (MMP) family are involved in the breakdown of extracellular matrix in normal physiological pr ocesses, such as embryonic development, reproduction Item Number: BIOV3523R-100 Unit of Measure: 100 MCG Packaging: Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	MBD1-Containing Chromatin-Associated Factor (MCAF) associates with methyl CpG-binding protein (MBD1) that functions to recruit methy ltransferases such as SETDB1 to chromatin. MCAF is required for the transcriptional repression and heterochr Item Number: BIOV3759-100 Unit of Measure: 100 4G Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	The BI-1 (Bax inhibitor 1) family is evolutionarily conserved as integral membrane proteins containing multiple membrane-spanning do mains that are predominantly localized to intracellular membranes. Item Number: BIOV3524-100 Unit of Measure: 100 MCG Packaging: Vial 347.00 CHF 347.0 CHF Aktuelle Lieferfrist auf Anfrage
Dystrophin is one of the actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin e xpression is found in muscle brain tissues, where it is located to the inner surface of the plasma membrane. Item Number: BIOV3586R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also p lays a role in intracellular calcium regulation by associating with three types of calcium release channel Item Number: BIOV3635-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Bcl-B (also called Bcl2-L-10) is a novel anti-apoptotic member of the Bcl-2 family. Bcl-B is closest in amino acid sequence homolog y to Boo protein. It contains four Bcl-2 homologs. Bcl-B mRNA is widely expressed in adult human tissues. Item Number: BIOV3695-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filam ents. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers Item Number: BIOV3525-100 Unit of Measure: 100 MCG Packaging: Vial 347.00 CHF 347.0 CHF Aktuelle Lieferfrist auf Anfrage
PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCg, PLCδ, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, Item Number: BIOV3587R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	GINSENOSIDE RB1, UoM: 1 * 250 mg Item Number: ACRO464632500 Unit of Measure: 250 MG Packaging: Glass bottle 346.00 CHF 346.0 CHF 1 in stock	APROTININ, UoM: 1 * 250 mg, CAS: 9087-70-1 Item Number: ICNA0219115883 Unit of Measure: 250 MG Packaging: Glasflasche für Feststoffe 2,210.00 CHF 2210.0 CHF Aktuelle Lieferfrist auf Anfrage	Highly expressed in cancer (Hec1) is a coiled-coil-enriched protein expressed abundantly in the S and M phases of rapidly dividing c ells where it localizes to the kinetochores. Hec1 is involved in spindle checkpoint signaling. Item Number: BIOV3763-100 Unit of Measure: 100 4G Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, -9 and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP’s ability to inhibit cell death. Item Number: BIOV3696-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRA Item Number: BIOV3764-100 Unit of Measure: 100 4G Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is o ne of 4 members of the NDRG α/β-hydrolase family. It is classified as a tumor suppressor and heavy metal-res Item Number: BIOV3526-100 Unit of Measure: 100 MCG Packaging: Vial 347.00 CHF 347.0 CHF Aktuelle Lieferfrist auf Anfrage	Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B, H, K, L, O, and S. The aspartyl protease class contains cathepsin D and E. Item Number: BIOV3588-100 Unit of Measure: 100 MCG Packaging: Vial 391.00 CHF 391.0 CHF Aktuelle Lieferfrist auf Anfrage

VWR / Merck Chemicals