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VWR / Merck Chemicals
Mammalian HDAC-8, isolated from human kidney, is a member of the histone deacetylase family. HDAC-8 shares homology with other HDACs in the family, but has different tissue distribution.
Item Number:
BIOV3608-100
Unit of Measure:
100 MCG
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
BROMELAIN--N/H, UoM: 1 * 1 kg, CAS: 37189-34-7
Item Number:
ICNA0210114291
Unit of Measure:
1 KG
Packaging:
Glasflasche für Feststoffe
2,170.00
CHF
2170.0
CHF
Current delivery time on request
LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation throμgh Rho-family GTPases and
Item Number:
BIOV3433-100
Unit of Measure:
100 MCG
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
PTEN (phosphatase and tensin homologue deleted on chromosome ten) phosphatase is a tumor suppressor gene implicated in a wide variet y of human cancers. PTEN encodes the 403 amino acid polypeptide originally described as a dual-specificity p
Item Number:
BIOV3479-100
Unit of Measure:
100 MCG
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essentia l for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembr
Item Number:
BIOV3555R-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
MAP kinase-activated protein kinase-2 (MAPKAPK-2), also known as p45 hsp27 kinase, is a 45-54 kDa serine-threonine protein kinase. M APKAPK-2 is rapidly phosphorylated and activated in response to stress, cytokines, and chemotactic factors.
Item Number:
BIOV3434-100
Unit of Measure:
100 MCG
Packaging:
Vial
410.00
CHF
410.0
CHF
Current delivery time on request
"p38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a
Item Number:
BIOV3438-100
Unit of Measure:
100 MCG
Packaging:
Vial
436.00
CHF
436.0
CHF
Current delivery time on request
Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been l inked to early onset of Alzheimer’s disease, probably functioning throμgh its associated g-secretase activit
Item Number:
BIOV3482-100
Unit of Measure:
100 MCG
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
HDAC family members have been divided into two classes. Class I of the HDACs comprises four members, HDAC-1, 2, 3, and 8, each of wh ich contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the
Item Number:
BIOV3609-100
Unit of Measure:
100 MCG
Packaging:
Vial
379.00
CHF
379.0
CHF
Current delivery time on request
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essentia l for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembr
Item Number:
BIOV3557-100
Unit of Measure:
100 4G
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
JMJD1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulat ion and influences transcriptional activation and suppression.
Item Number:
BIOV3439-100
Unit of Measure:
100 MCG
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
Rab5 is a 24 kDa GTP-binding protein that is localized to the cytoplasmic side of the plasma membrane, clathrin-coated vesicles, and early endosomes. Rab5 is believed to regulate vesicle fusion throμgh a cycle of GDP/GTP exchange and GTP hy
Item Number:
BIOV3483-100
Unit of Measure:
100 MCG
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
POLY-L-LYSINE HBR (MW 4,000 -15,000), UoM: 1 * 1 g
Item Number:
ICNA0210269191
Unit of Measure:
1 G
Packaging:
Amber Glass Bottle
2,180.00
CHF
2180.0
CHF
Current delivery time on request
The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of le ucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain.
Item Number:
BIOV3558R-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Tumor Endothelial Markers (TEMs, TEM 1-9) are recently identified genes, whose expression is elevated in tumor-associated endotheliu m. TEMs are barely detectable in normal endothelial cells. TEM8 has been shown to interact with C5 domain of
Item Number:
BIOV3668-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
HDAC family are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold lar
Item Number:
BIOV3610-100
Unit of Measure:
100 MCG
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essentia l for Toll-induced signal transduction. TLR9 has been sμggested as a receptor for unmethylated CpG dinucleot
Item Number:
BIOV3559R-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasmino gen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminog
Item Number:
BIOV3440-100
Unit of Measure:
100 MCG
Packaging:
Vial
373.00
CHF
373.0
CHF
Current delivery time on request
p70 S6 kinase and p90 Rsk kinase are the two distinct 40S ribosomal protein S6 Ser/Thr kinases present in somatic animal cells. p90 Rsk kinase is maximally activated within minutes of addition of growth factors or phorbol ester to cultured
Item Number:
BIOV3485-100
Unit of Measure:
100 MCG
Packaging:
Vial
335.00
CHF
335.0
CHF
Current delivery time on request
Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of ce ll growth and differentiation. Activation of MAP kinases occurs throμgh phosphorylation of threonine and tyr
Item Number:
BIOV3441-100
Unit of Measure:
100 MCG
Packaging:
Vial
410.00
CHF
410.0
CHF
Current delivery time on request
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