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Apoptosis plays an important role in many cellular processes. Dio-1 (Death Inducer-O bliterator-1), a putative transcription factor, has been indicated to function in the onset of apoptosis. Dio-1 expression is upregulated when an apoptosis Item Number: BIOV3592-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	ASH2 (absent, small, or homeotic discs 2) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. ASH2 associates with a multi Item Number: BIOV3772-100 Unit of Measure: 100 4G Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Steroid receptor coactivator 3 (SRC3) belongs to the SRC family of proteins that interacts with nuclear receptors to facilitate tran scription. The 3 homologous members of this family are SRC-1 (NCoA-1), SRC-2 (GRIP1, TIF2, or NcoA-2) Item Number: BIOV3773-100 Unit of Measure: 100 4G Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Liver X receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once Item Number: BIOV3641-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request
CLOZAPINE, UoM: 1 * 1 g, CAS: 5786-21-0 Item Number: ACRO464280010 Unit of Measure: 1 G Packaging: Glass bottle 323.00 CHF 323.0 CHF Current delivery time on request	Extracellular stimuli such as growth factors and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun de pendent transcription. Mutation at Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced sign Item Number: BIOV3702-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, Item Number: BIOV3774-100 Unit of Measure: 100 4G Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular w eights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. Item Number: BIOV3593-100 Unit of Measure: 100 MCG Packaging: Vial 391.00 CHF 391.0 CHF Current delivery time on request
Serine/threonine-protein kinase TAO1 is an enzyme that in humans is encoded by the TAOK1 gene Item Number: BIOV3776-100 Unit of Measure: 100 4G Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	Thyroid receptor interacting protein 1 (TRIP1) was originally identified as a protein that interacts with the thyroid receptor and i s homologous to the yeast SUG1 protein, a transcriptional coactivator. It was later identified as an ATPase Item Number: BIOV3775-100 Unit of Measure: 100 4G Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	BIF-1 (Bax interacting factor-1) is a 365 amino acid protein that interacts with Bax protein and influences cell survival and death. BIF-1 contains a Src homology 3 (SH3) domain in the C-terminus. Overexpression of BIF-1 promotes Bax Item Number: BIOV3704-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Serine/threonine-protein kinase TAO1 is an enzyme that in humans is encoded by the TAOK1 gene Item Number: BIOV3776R-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor bindi ng. Syndecan-1 is an matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Item Number: BIOV3644-100 Unit of Measure: 100 MCG Packaging: Vial 391.00 CHF 391.0 CHF Current delivery time on request	TUCAN (Tumor Up-regulated Card-containing Antagonist of Caspase-Nine) is a CARD (Caspase-Associated Recruitment Domains) containing protein that binds and suppresses activation of pro-Caspase-9 and found to be overexpressed in some types Item Number: BIOV3705-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Plasma phospholipid transfer protein (PLTP) plays a central role in regulating plasma HDL levels and distribution of HDL subpopulati ons. This regulation is evidenced in vivo by markedly reduced plasma HDL levels in PLTP gene knock-out mice. Item Number: BIOV3595-100 Unit of Measure: 100 MCG Packaging: Vial 322.00 CHF 322.0 CHF Current delivery time on request	Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix Item Number: BIOV3645A-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request
Galectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions, as w ell as apoptosis. Galectin-1 has the ability to induce apoptosis of activated T-cells and T-leukaemia cell l Item Number: BIOV3596-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair protein that response to DNA damage by removing methly or alkyl group s from the O6 position of guanine. MGMT protects normal cells from cytotoxic effects Item Number: BIOV3820-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Current delivery time on request	Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix Item Number: BIOV3645R-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Current delivery time on request	FMOC-HIS(TRT)-OH NOVABIOCHEM, UoM: 1 * 2 kg Item Number: NOVA8.52032.2000 Unit of Measure: 2 KG Packaging: Plastic bottle 3,170.00 CHF 3170.0 CHF Current delivery time on request

VWR / Merck Chemicals