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VWR / Merck Chemicals

NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK w as initially isolated from a human B cell cDNA library and contains 795 amino acids with an apparent molecul
Item Number: BIOV3193R-100
Unit of Measure: 100 MCG
Packaging: Vial
322.00 CHF 322.0 CHF
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FATP4 is a transmembrane protein that is involved in the uptake and metabolism of long chain fatty acids. FATP4 has acyl-CoA synth ase activity and contains an AMP-binding motif. FATP4 is linked to insulin resistance and metabolic disorde
Item Number: BIOV3268-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
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The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 forms homo dimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr6
Item Number: BIOV3359-100
Unit of Measure: 100 MCG
Packaging: Vial
410.00 CHF 410.0 CHF
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Bad is a member of the Bcl-2 family protein that selectively dimerize with Bcl-xL and Bcl-2 resulting in cell death. Survival factor s such as IL-3 can inhibit the apoptotic activity of Bad by activating intracellular signaling pathways that
Item Number: BIOV3269-100
Unit of Measure: 100 MCG
Packaging: Vial
410.00 CHF 410.0 CHF
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Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellula r signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors
Item Number: BIOV3360R-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
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Histone-lysine N- methyltransferase SETD3 has a function as methylation of Lys36 of histone H3 which represents a specific tag for e pigenetic transcriptional activation. It is highly expressed in muscular tissues.
Item Number: BIOV3197-200
Unit of Measure: 200 MCG
Packaging: Vial
347.00 CHF 347.0 CHF
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encod es hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-
Item Number: BIOV3198-100
Unit of Measure: 100 MCG
Packaging: Vial
360.00 CHF 360.0 CHF
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Tumor Necrosis Factor-alpha (TNF-α) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and cer tain other target cells. Rat TNF-α is a 17 kDa protein containing 157 amino acid residues.
Item Number: BIOV3054-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
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Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control , DNA replication and chromatin organization.
Item Number: BIOV3267-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
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Arginine methylation is an important protein modification catalyzed by arginine methyltransferase such as PRMT7. PRMT7 has two methy ltransferase domains each containing a putative AdoMet binding motif.
Item Number: BIOV3059-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
Aktuelle Lieferfrist auf Anfrage
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression.
Item Number: BIOV3199-100
Unit of Measure: 100 MCG
Packaging: Vial
347.00 CHF 347.0 CHF
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Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thoμght to play an important role in embryogenesis and development. BLCAM α and BLCAM β are p
Item Number: BIOV3363-100
Unit of Measure: 100 MCG
Packaging: Vial
322.00 CHF 322.0 CHF
Aktuelle Lieferfrist auf Anfrage
Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death .
Item Number: BIOV3201-100
Unit of Measure: 100 MCG
Packaging: Vial
335.00 CHF 335.0 CHF
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Apoptosis can be induced by certain cytokines including TNF and Fas Ligand of the TNF super-family throμgh their death domain (DD) c ontaining receptors, TNFR1 and Fas.
Item Number: BIOV3061R-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
Aktuelle Lieferfrist auf Anfrage
MAK10 protein regulates the proliferation of smooth muscle cells. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species.
Item Number: BIOV3134-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
Aktuelle Lieferfrist auf Anfrage
RIP (Receptor Interacting Protein) is a 74 kDa Ser/Thr kinase which interacts with CD95 (Fas/Apo1) receptor and the tumor necrosis f actor receptor (TNFR1). It is a cell death domain adapter protein which can bind to the adapter proteins TRA
Item Number: BIOV3279-100
Unit of Measure: 100 MCG
Packaging: Vial
322.00 CHF 322.0 CHF
Aktuelle Lieferfrist auf Anfrage
Caspase-7 is a 34 kDa protein consisting of two subunits and a short prodomain. The procaspase-7 can be activated by cleavage by ups tream caspases to form active caspase-7 in apoptosis.
Item Number: BIOV3135-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
Aktuelle Lieferfrist auf Anfrage
The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD1 (methyl-CpG binding domain protein 1) binds to methylated CpG sites and represses gene transcription.
Item Number: BIOV3281-100
Unit of Measure: 100 MCG
Packaging: Vial
309.00 CHF 309.0 CHF
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This antibody reacts with the Stage-specific embryonic antigen-3 (SSEA-3). The epitope is expressed on the surface of human teratoca rcinoma stem cells , embryonic carcinoma (EC) cells, human embryonic germ(EG) cells and human embryonic stem
Item Number: BIOV3065-25
Unit of Measure: 25 MCG
Packaging: Vial
272.00 CHF 272.0 CHF
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Nestin may play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daμghter cells d uring progenitor cell division (By similarity).
Item Number: BIOV3208-100
Unit of Measure: 100 MCG
Packaging: Vial
360.00 CHF 360.0 CHF
Aktuelle Lieferfrist auf Anfrage