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The phosphodiesterase type-3 (PDE3) family is comprised of 2 isoforms, PDE3A and PDE3B.Phosphodiesterases (PDE) are crucial in the r egulation of the intracellular level of the second messenger cAMP by hydrolyzing cAMP to 5’AMP. Item Number: BIOV3956-200 Unit of Measure: 200 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Rictor is a component of a protein complex [mTORC2] that integrates nutrient- and growth factor-derived signals to regulate cell gro wth. Rictor also plays an essential role in Akt phosphorylation and signaling. Item Number: BIOV3957-200 Unit of Measure: 200 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Rabex-5, also called RabGEF1 and RAP1, was identified as a guanine nucleotide exchange factor (GEF) for Rab5, a member of the Ras su perfamily of small Rab GTPases (1). Rabex-5 generates the GTP-bound active form of Rab5 and forms a tight as Item Number: BIOV3905-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	SUMATRIPTAN SUCCINATE, UoM: 1 * 1 g, CAS: 103628-48-4 Item Number: ACRO462420010 Unit of Measure: 1 G Packaging: Glass bottle 225.00 CHF 225.0 CHF 3 in stock
Brij(R) 35, UoM: 1 * 12 kg, CAS: 9002-92-0 Item Number: SPCMBR105-12KG Unit of Measure: 12 KG Packaging: Poly Pail 1,340.00 CHF 1340.0 CHF Aktuelle Lieferfrist auf Anfrage	The Firefly luciferase is a genetically modified variant derived from the Luciferase of Diaphanes pectinealis endemic to Yunnan prov ince, China. It has been modified to provide enhanced stability compared to the normal phenotype of Photinus Item Number: BIOV3848-500 Unit of Measure: 500 MCG Packaging: Vial 322.00 CHF 322.0 CHF Aktuelle Lieferfrist auf Anfrage	Proteinase inhibitor 6 (PI-6) is a 42 kDa cytoplasmic protein belonging to the serine proteinase inhibitor (serpin) super family and the ovalbumin-serpin super family. Sequence similarity sμggests that PI-6 most resembles the ovalbumin serp Item Number: BIOV3849-100 Unit of Measure: 100 MCG Packaging: Vial 373.00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage	Calmodulin binding peptide (CBP) tag is a fusion protein that is useful for immunoaffinity purification of proteins expressed in E.c oli. The CBP tag binds to calmodulin resin in the presence of low concentration of calcium and can be elute Item Number: BIOV3960-100 Unit of Measure: 100 MCG Packaging: Vial 373.00 CHF 373.0 CHF Aktuelle Lieferfrist auf Anfrage
SREBP (Sterol Regulatory Element Binding Protein) 1 and 2 are transcription factors th at regulates cholesterol homeostasis. SREBP p roteins are attached to the endoplasmic reticulum and nuclear envelope. SREBP proteins undergo proteolytic c Item Number: BIOV3961-100 Unit of Measure: 100 MCG Packaging: Vial 328.00 CHF 328.0 CHF Aktuelle Lieferfrist auf Anfrage	TSC2 is important in regulating cell proliferation and tumor development. Mutations in either the TSC1 or TSC2 tumor suppressor gene s caused tuberous sclerosis complex (TSC), an autosomal dominant tumor syndrome. Item Number: BIOV3962-200 Unit of Measure: 200 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Ficolin-1 also known as M-Ficolin is a pattern recognition molecule of the lectin complement activation pathway. It is expressed mos tly in monocytes, nuetrophils and in type II alveolar epithelial cells. Ficolin-1 is detected on the surface Item Number: BIOV3852-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix compon ents, including collagen, gelatin, fibronectin, laminin and proteoglycan. Item Number: BIOV3969-200 Unit of Measure: 200 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
Actin is expressed in all eukaryotic cells and is the major component of the cytoskeleton. At least six types of actin are present i n mammalian tissues and fall into three classes. Item Number: BIOV3917-100 Unit of Measure: 100 MCG Packaging: Vial 335.00 CHF 335.0 CHF Aktuelle Lieferfrist auf Anfrage	BAICALIN, UoM: 1 * 5 g, CAS: 21967-41-9 Item Number: ACRO464900050 Unit of Measure: 5 G Packaging: Glass bottle 83.20 CHF 83.2 CHF 4 in stock	RETIGABINE DIHYDROCHLORIDE, UoM: 1 * 1 g Item Number: ACRO465010010 Unit of Measure: 1 G Packaging: Glass bottle 758.00 CHF 758.0 CHF Aktuelle Lieferfrist auf Anfrage	Stress-activated map kinase-interacting protein 1 or Sin1 is required for Rictor binding in the mTORC2 complex. Sin1 is also a scaff olding protein in SAPK (stress-activated kinase) signaling and JNK signaling pathway. Item Number: BIOV3971-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage
High density lipoprotein-binding protein (HDLBP) or Vigilin is a protein that plays a role in the regulation and delivery of fat to cells for energy and storage. HDLBP binds HDL molecules and may function in the elimination of excess cellul Item Number: BIOV3853-100 Unit of Measure: 100 MCG Packaging: Vial 309.00 CHF 309.0 CHF Aktuelle Lieferfrist auf Anfrage	Insulin-induced gene (InSig) localizes in the endoplasmic recticulum(ER) and is highly expressed in the liver and fibroblast cell li nes. InSig1 and InSig2 play important roles in the regulation of cholesterol biosynthesis. Item Number: BIOV3854-100 Unit of Measure: 100 MCG Packaging: Vial 366.00 CHF 366.0 CHF Aktuelle Lieferfrist auf Anfrage	Streptavidin Binding Peptide (SBP) tag is very versatile and can be inserted into expression vectors for easy detection of recombina nt proteins and purification by use of affinity columns. The full sequence for SBP-tag is 38 amino acids lon Item Number: BIOV3986-100 Unit of Measure: 100 MCG Packaging: Vial 385.00 CHF 385.0 CHF Aktuelle Lieferfrist auf Anfrage	This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a t ranscription factor and may play a role in brain and sensory organ development. Item Number: BIOV3919-100 Unit of Measure: 100 MCG Packaging: Vial 360.00 CHF 360.0 CHF Aktuelle Lieferfrist auf Anfrage

VWR / Merck Chemicals