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VWR / Merck Chemicals
Calsenilin is also known as DREAM and KChlP3. Calsenilin interacts with presenilin-2, a protein involved in Alzheimer’s disease, to reverse presenilin mediated enhancement of calcium signaling. Calsenilin also has pro-apoptotic function, is
Item Number:
BIOV3706-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
The import of proteins from the cytoplasm to the nucleus involves docking the protein to receptors associated with the nuclear pore complex followed by translocation through the nuclear pore. RCH1 is an adaptor protein
Item Number:
BIOV3779-100
Unit of Measure:
100 4G
Packaging:
Vial
436.00
CHF
436.0
CHF
Current delivery time on request
It is expected that the His-Tag monoclonal antibody will react with proteins tagged with His from all species.
Item Number:
BIOV3646-100
Unit of Measure:
100 MCG
Packaging:
Vial
373.00
CHF
373.0
CHF
Current delivery time on request
Steroid receptor RNA activator (SRA) selectively mediates transactivation of steroid hormone receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed
Item Number:
BIOV3780-100
Unit of Measure:
100 4G
Packaging:
Vial
436.00
CHF
436.0
CHF
Current delivery time on request
FMOC-TRP-OH, UoM: 1 * 1 kg, CAS: 35737-15-6
Item Number:
NOVA8.52207.1000
Unit of Measure:
1 KG
Packaging:
Glass bottle for solids
1,270.00
CHF
1270.0
CHF
Current delivery time on request
Sox proteins are related to mammalian sex deternining gene that encodes DNA-binding protein. About 30 SOX family proteins have been identified. Sox-1 is a transcription factor that is found in the embryonic nervous system.
Item Number:
BIOV3822-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Cyr61 is a member of angiogenic and vasculogenic regulators designated CCN proteins, which includes CTGF, Cyr61 homolog, Fisp2. Cyr6 1 functions as an angiogenic inducer, stimulating cell adhesion and migration and promotes DNA synthesis
Item Number:
BIOV3648-100
Unit of Measure:
100 MCG
Packaging:
Vial
391.00
CHF
391.0
CHF
Current delivery time on request
HDAC1 is an active component of transcriptional corepressor complexes which can be recruited to specific promoter regions via transc riptional factors. HDAC1 catalyzes removal of acetyl-groups from acetyl-lysines of histones
Item Number:
BIOV3601-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
Microtubules are one type of cytoskeleton. Globular tubulin subunits are the building blocks of a microtubule and the α and β-tubuli n heterodimer forms the tubulin subunits, which is present in all eukaryotic cells. Microtubules mediate man
Item Number:
BIOV3708-100
Unit of Measure:
100 MCG
Packaging:
Vial
366.00
CHF
366.0
CHF
Current delivery time on request
The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcin omas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER
Item Number:
BIOV3782-100
Unit of Measure:
100 4G
Packaging:
Vial
436.00
CHF
436.0
CHF
Current delivery time on request
Tyrosine hydroxylase play an important role in the synthesis of dopamine and other catecholamines. The enzyme’s activity is regulate d in the level of transcription and translation, as well as posttranscriptional modifications.
Item Number:
BIOV3649-100
Unit of Measure:
100 4G
Packaging:
Vial
436.00
CHF
436.0
CHF
Current delivery time on request
FMOC-ALA-THR(PSIME,MEPRO)-OH (BULK), UoM: 1 * 25 g, CAS: 252554-79-3
Item Number:
8.52180.0025
Unit of Measure:
25 G
Packaging:
Glass bottle
1,140.00
CHF
1140.0
CHF
Current delivery time on request
FMOC-ALA-THR(PSIME,MEPRO)-OH, UoM: 1 * 100 g
Item Number:
NOVA8.52180.0100
Unit of Measure:
100 G
Packaging:
Glass bottle
3,040.00
CHF
3040.0
CHF
Current delivery time on request
BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development
Item Number:
BIOV3823-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
HDAC2 is a class I mammalian histone deacetylase containing 488 amino acid residues with an apparent size of ~55 kDa by denaturing S DS-PAGE. HDAC2 has been shown to interact directly with transcription repressor complexes
Item Number:
BIOV3602-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
MARCKS (Myristoylated alanine-rich protein kinase C substrate) is a major PKC substrate that is distributed in various cell types. M ARCKS has been implicated in cell motility, cell adhesion, phagocytosis, membrane traffic and mitogenesis. P
Item Number:
BIOV3650-100
Unit of Measure:
100 MCG
Packaging:
Vial
436.00
CHF
436.0
CHF
Current delivery time on request
FOXP3 a member of the forkhead/winge-helix family of transcriptional regulators and is highly conserved in humans. It has been propo sed that FOXP3 may be a master regulatory gene and marker for Treg cells. Recent reports also sμggest expres
Item Number:
BIOV3709-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to b alance nutrient availability and cell growth.
Item Number:
BIOV3786-100
Unit of Measure:
100 4G
Packaging:
Vial
436.00
CHF
436.0
CHF
Current delivery time on request
EGF-like module-containing mucin-like receptor 2 (EMR2) is a member of the class B seven-span transmembrane (TM7) receptor family. E MR2 is expressed predominantly by cells of the immune system such as leukocytes.
Item Number:
BIOV3652-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCg, PLCd, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors,
Item Number:
BIOV3710-100
Unit of Measure:
100 MCG
Packaging:
Vial
309.00
CHF
309.0
CHF
Current delivery time on request
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