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AZD-1283 is a potent antagonist of the P2Y12 receptor. In a modified Folts model in dog, AZD-1283 dose-dependently induces increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED₅₀ value of 3.0 μg/kg/min. Item Number: BIOV2838-25 Unit of Measure: 25 MG 473.00 CHF 473.0 CHF Current delivery time on request	PF-03394197 is potent and selective Janus kinase (JAK) inhibitor. It inhibits JAK family members with an IC₅₀ of 10-99 nM being most potent against JAK1 (IC₅₀ = 10 nM). PF-03394197 does not inhibit a panel of 38 non-JAK kinases (IC₅₀ >1 µM). Display Item Number: BIOV2883-5 Unit of Measure: 5 MG 183.00 CHF 183.0 CHF Current delivery time on request	KRN-633 is a cell-permeable, reversible, and ATP-competitive inhibitor of VEGFR kinase activity (IC₅₀ values of 170 nM, 160 nM, and 125 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively). Item Number: BIOV2839-25 Unit of Measure: 25 MG 473.00 CHF 473.0 CHF Current delivery time on request	L-902,688, UoM: 1 * 10 mg, CAS: 634193-54-7 Item Number: CAYM10007712-10 Unit of Measure: 10 MG 3,030.00 CHF 3030.0 CHF Current delivery time on request
PODXL, also known as Podocalyxin, is a heavily glycosylated transmembrane sialoprotein in the CD34 and endoglycan family. This prote in involved in the regulation of both adhesion and cell morphology and cancer progression. Item Number: BIOVP1033-10 Unit of Measure: 10 MCG 133.00 CHF 133.0 CHF Current delivery time on request	Potent and selective inhibitor of CYP3A (IC50 = 30 nM (CYP3A4), 17 μM (CYP3A5) and 70 μM (CYP3A7). Item Number: BIOV2917-5 Unit of Measure: 5 MG 133.00 CHF 133.0 CHF Current delivery time on request	PODXL, also known as Podocalyxin, is a heavily glycosylated transmembrane sialoprotein in the CD34 and endoglycan family. This prote in involved in the regulation of both adhesion and cell morphology and cancer progression. Item Number: BIOVP1033-50 Unit of Measure: 50 MCG 625.00 CHF 625.0 CHF Current delivery time on request	SD208 is a potent, ATP-competitive transforming growth factor-β receptor 1 (TGF-βR1) kinase inhibitor (IC₅₀ = 49 nM). Displays > 100 -fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively. Exhibits anti-inflammatory and a Item Number: BIOV2885-5 Unit of Measure: 5 MG 171.00 CHF 171.0 CHF Current delivery time on request
CF405M azide, UoM: 1 * 0,5 mg Item Number: 92092. Unit of Measure: 0,500 MG 585.00 CHF 585.0 CHF Current delivery time on request	Baricitinib is a selective JAK1 and JAK2 inhibitor with IC₅₀ values of 5.9 nM and 5.7 nM, respectively. Baricitinib is ~70 and ~10- fold selective versus JAK3 and Tyk2, with no inhibition to c-Met and Chk2. Item Number: BIOV2842-50 Unit of Measure: 50 MG 574.00 CHF 574.0 CHF Current delivery time on request	S100B also known as protein S100-B. S100B is a protein of the S100 protein family. S100 proteins comprise a multigene family of EF- hand calcium binding proteins that engage in multiple functions in response to cellular stress. Item Number: BIOVP1035-10 Unit of Measure: 10 MCG 133.00 CHF 133.0 CHF Current delivery time on request	Cell invasion is the ability of cells to migrate from one area to another through an extracellular matrix. Cell invasion is exhibite d by both normal cells as well as cancerous cells in response to specific external signals, including chemical & mech Item Number: BIOVK919-24 Unit of Measure: 24 AS 537.00 CHF 537.0 CHF Current delivery time on request
CAY10717, UoM: 1 * 10 mg, CAS: 1240322-54-6 Item Number: CAYM19955-10 Unit of Measure: 10 MG 697.00 CHF 697.0 CHF Current delivery time on request	PF-04554878 is potent, ATP-competitive, focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activ ities. PF-04554878 inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. A combinati Item Number: BIOV2888-25 Unit of Measure: 25 MG 877.00 CHF 877.0 CHF Current delivery time on request	2X PCR MasterMix with dye Item Number: BIOVM1137-200 Unit of Measure: 200 ST 284.00 CHF 284.0 CHF Current delivery time on request	HEATING ELEMENT 3KW 220V, UoM: 1 * 1 items Item Number: 171-1036 Unit of Measure: 1 ST 603.00 CHF 603.0 CHF Current delivery time on request
Ep-CAM/CD326(HEA125),Biotinconjugate,0.1mg/mL Item Number: BNCB0825-500 Unit of Measure: 500 4G 620.00 CHF 620.0 CHF Current delivery time on request	CD45RB(BRA-55),CF680Rconjugate,0.1mg/mL Item Number: BNC810313-100 Unit of Measure: 100 4G 225.00 CHF 225.0 CHF Current delivery time on request	FLASK FLAT BOTTOM BOROSILICATE 500ML, UoM: 1 * 20 items Item Number: BIBBFF500/2S Unit of Measure: 20 ST 703.00 CHF 703.0 CHF Current delivery time on request	Taq DNA Polymerase Item Number: BIOVM1148-250 Unit of Measure: 250 LE 391.00 CHF 391.0 CHF Current delivery time on request

VWR / Merck Chemicals