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  3. AMG232 is a highly potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC₅₀ = 9.1 nM), with remarkable pharmacokinetic properties a nd in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED₅₀ = 9.1 mg/kg).

AMG232 is a highly potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC₅₀ = 9.1 nM), with remarkable pharmacokinetic properties a nd in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED₅₀ = 9.1 mg/kg).

Item Number: BIOV9556-5
Unit of Measure: 5 MG
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404.00 CHF

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    CAS Number: 1352066-68-2
    Manufacturer: BIOVISION
    Manufacturer Number: 9556-5
    Chemical Formula: C28H35Cl2NOS
    Storage Temperature: Freezer (-20)

    AMG-232 ≥98%