GN25 blocks Snail binding to p53 and induces p53 expression in cancer cells in a KRas dependent manner. Oncogenic KRas has been show n to inhibit p53 function by inducing Snail to bind and eliminate p53 through exocytosis.

Item Number: BIOV9430-5
Unit of Measure: 5 MG
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    Manufacturer: BIOVISION
    Manufacturer Number: 9430-5
    Storage Temperature: Freezer (-20)

    GN25 blocks Snail binding to p53 and induces p53 expression in cancer cells in a KRas dependent manner. Oncogenic KRas has been show n to inhibit p53 function by inducing Snail to bind and eliminate p53 through exocytosis.