RAF265 (CHIR-265) is a potent and selective inhibitor of C-Raf/B-Raf/B-Raf V600E (IC₅₀ of 3-60 nM); displays potent inhibition on VE GFR2 phosphorylation with EC₅₀ of 30 nM. RAF265 inhibits the growth of advanced human melanoma tumors.

Item Number: BIOV2856-5
Unit of Measure: 5 MG
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    Manufacturer: BIOVISION
    Manufacturer Number: 2856-5
    Storage Temperature: Freezer (-20)

    RAF265 (CHIR-265) is a potent and selective inhibitor of C-Raf/B-Raf/B-Raf V600E (IC₅₀ of 3-60 nM); displays potent inhibition on VE GFR2 phosphorylation with EC₅₀ of 30 nM. RAF265 inhibits the growth of advanced human melanoma tumors.