IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.

Item Number: BIOV2822-25
Unit of Measure: 25 MG
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    CAS Number: 1129669-05-1
    Manufacturer: BIOVISION
    Manufacturer Number: 2822-25
    Chemical Formula: C22H20FN3O2
    Storage Temperature: Freezer (-20)

    IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.